omen in labor may suffer needlessly
because doctors mistakenly advise them to delay a common pain
treatment for fear that it will impede contractions and lead to a
Caesarean section, researchers are reporting.
A new study of the treatment - a type of anesthesia that injects
painkiller into the spinal fluid and the epidural area around the
spinal cord to numb the pelvic region - finds that giving it early
or late in labor makes no difference in Caesarean rates among women
having first babies.
There is no reason for women to deny themselves the medicine or
for doctors to withhold it, the study says.
Other researchers urged caution, noting that not all hospitals
offer such combined anesthesia and that the findings might not apply
to all epidural treatments.
About 60 percent of American women have epidural anesthesia
during childbirth. Dr. Cynthia A. Wong, the lead author of the new
study and an obstetric anesthesiologist at Northwestern Memorial
Hospital in Chicago, said women were often pressured to delay the
treatment and made to feel guilty or weak if they asked for one too
soon.
"Women say: 'I must be a wimp. I had to ask for pain medication
so early,' " Dr. Wong said. "If they're wimps, we're all wimps."
The study appears today in The New England Journal of
Medicine.
The American College of Obstetricians and Gynecologists
recommends that for first-time mothers epidurals be delayed "when
feasible" until the cervix dilates to at least four or five
centimeters, or one and a half to two inches.
It can take many hours to reach that point. In the meantime, the
college says, other painkillers like narcotics should be given as
injections. The college hedges its bets, adding that if a woman asks
for an epidural, she should have it, no matter how early.
The advice to postpone epidurals was based on studies that
suggested that they were associated with higher Caesarean rates,
especially if given early in labor. The findings led some doctors to
suspect that the epidurals were slowing contractions or making women
too weak to push.
Other researchers said women who had so much pain that they
wanted epidurals early in labor probably had something abnormal
occurring and that it was the underlying problem that led to
Caesareans. Those questions have not been fully resolved.
In recent years, anesthesiologists have used smaller drug doses
and mixed techniques in hopes of easing pain while leaving a woman
able to move and push at delivery time.
Dr. Wong's study included 750 women who were in labor and giving
birth for the first time. All had cervical dilation less than four
centimeters. The women were randomly picked to receive a narcotic
shot or a spinal anesthetic the first time they asked for medicine.
A spinal usually works with a smaller dose of medicine than in an
epidural.
At the next request for pain medicine, the women who had received
spinals were given epidurals. That was done because a spinal is not
usually repeated. The women who had received narcotics were given
repeat shots. After that, the narcotics group was given epidurals
when reaching four centimeters or more, or when asking for more
medicine.
The Caesarean rate in the women who started with spinals was 17.8
percent. For the women given narcotics, it was 20.7 percent, a
statistically insignificant difference. It was significant, however,
that the women with spinals had shorter labors, by an hour and a
half, and felt less pain.
"The bottom-line message," Dr. Wong said, "is that if you're a
first-time mom in early labor and it hurts and you need pain
medicine, by getting this kind of spinal-epidural, you're not at
increased risk for a Caesarean, and there are benefits to doing it
this way."
Dr. Laura E. Riley, director of labor and delivery at
Massachusetts General Hospital in Boston, had words of caution.
"They do a very intricate kind of analgesia," Dr. Riley said,
referring to the combined spinal and epidural technique. "I don't
know that many places that can do it."
The findings may not apply to other patients who have standard
epidurals without the spinal component or epidurals that use
different drugs from the ones in the study.
"It may just pertain to this group of patients," Dr. Riley said.
"It's not clear that this is really generalizable."
Dr. Riley, chairwoman of a committee on practice standards for
the college of obstetrics, said she did not think that the group
would change its position based on the new study.
"I don't think it's enough of a groundbreaking, 'Omigosh!' kind
of result," she said.
Dr. William Camann, an anesthesiologist at Brigham and Women's
Hospital, also in Boston, wrote an editorial accompanying the study
agreeing with Dr. Wong. He said women were forced to endure extra
hours of pain for no reason and given narcotics that did not work
well and that had harmful side effects for mothers and babies.
"Women in labor," Dr. Camann wrote, "deserve to have as many
options as possible at their disposal to ensure a safe and
satisfying birth experience both for themselves and for their
infants."